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Updated: Sep 9, 2025

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向KEAP1/NRF2的相互作用通过抑制巨铁减轻了动脉样硬化

Xinxin Zhu1, Yuwu Chen1, Biyi Xu1

  • 1Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), No. 246 Xuefu Road, Nangang District, Harbin, 150001, China; The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, 150001, China.

Free radical biology & medicine
|August 30, 2025
PubMed
概括

通过防止巨细胞亡,奥莱uropein (OL) 能够预防动脉样硬化. 它通过竞争性结合KEAP1来增强NRF2激活,为这种动脉疾病提供了新的治疗策略.

关键词:
动脉样硬化铁症巨细胞NRF2/KEAP1复合体类植物

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