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Updated: Sep 9, 2025

Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
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Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment

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通过吸入RNA进行增强肺癌免疫疗法的调节瘤原纤维对齐

Bin Hu1,2, William Stewart3, Qijing Chen1,2

  • 1Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, China.

Nature communications
|August 30, 2025
PubMed
概括

这项研究引入了使用脂质纳米颗粒 (LNP) 的可吸入疗法,以直接向肺癌提供治疗. 这种新的方法通过修改瘤微环境 (TME) 和改善T细胞活性来提高免疫疗法的有效性.

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