与胃癌风险相关的饮食单不和脂肪酸
Ngoan Tran Le1, Yen Thi-Hai Pham2,3,4, Linh Thuy Le5
1Institute of Research and Development, Duy Tan University, Da Nang, Vietnam.
European journal of nutrition
|August 31, 2025
概括
在越南,高摄入单不和脂肪酸 (MUFA) 与胃癌风险降低有关. 这些发现表明富含MUFA的饮食可能有助于预防胃癌,特别是在资源有限的环境中.
科学领域:
- 营养科学
- 胃肠病学
- 癌症学
背景情况:
- 单不和脂肪酸 (MUFA) 具有抗氧化和降胆固醇等有益特性.
- 关于MUFA摄入量和胃癌风险的现有证据在不同人群中不一致.
- 饮食模式因种族而异,需要对特定人群进行研究.
研究的目的:
- 研究MUFA消费与胃癌风险之间的关联.
- 评估越南人口中的这种关系,考虑到饮食成分的潜在种族差异.
主要方法:
- 一项基于医院的病例对照研究对1182例胃癌病例和2965例对照进行.
- 使用经过验证的半量化食物频率问卷 (FFQ) 评估了单不和脂肪酸 (MUFA) 的摄入量.
- 使用无条件逻辑回归模型计算几率 (OR) 和95%置信区间 (CI).
主要成果:
- 观察到MUFA摄入量与胃癌风险之间的反向关联 (每次SD增加的OR=0. 75;P趋势< 0. 001).
- 摄入MUFA的较高五分位数显示胃癌的几率逐渐降低,最高五分位数的OR为0. 43 (95% CI为0. 33- 0.57).
- 这种反向关系在两性和不同年龄组 (60岁以下和60岁以上) 都是一致的.
结论:
- 单不和脂肪酸 (MUFA) 的摄入与越南人口的胃癌风险降低有关.
- 无论性别或年龄,都观察到MUFA的保护作用.
- 这些发现对低收入和中等收入国家和类似资源有限的地区的胃癌预防策略有重大影响.
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