相关实验视频

Updated: Sep 9, 2025

A Simplified Technique for Producing an Ischemic Wound Model

A Simplified Technique for Producing an Ischemic Wound Model

Published on: May 2, 2012

使用踏板加速时间预测糖尿病患者的缺血性伤口愈合

Eduardo Silva¹, Joana Iglésias¹, Pedro Lima²

¹Department of Angiology and Vascular Surgery, Coimbra Local Health Unit, Coimbra, Portugal.

Portuguese journal of cardiac thoracic and vascular surgery

|August 31, 2025

概括

在患有周围动脉疾病的糖尿病患者中,踏板加速时间 (PAT) 有效预测伤口愈合. 180毫秒或更低的PAT表示良好的愈合潜力,而更高的值则与截肢等更糟糕的结果相关.

科学领域:

血管医学
糖尿病学
创伤治愈研究

背景情况:

糖尿病是外周动脉疾病 (PAD) 的主要驱动因素,通常导致中枢动脉化.
由于化,糖尿病患者的脚指数 (ABI) 是有限的.
踩踏加速时间 (PAT) 通过测量脚动脉的缩加速提供了一个诊断替代方案.

研究的目的:

验证踏板加速时间 (PAT) 作为PAD糖尿病患者伤口愈合的预测指标.
评估PAT预测需要重新血管或截肢的能力.
在该患者群体中确认已确定的180毫秒PAT切断值.

主要方法:

对患有PAD和下肢伤害的糖尿病患者进行了回顾性截面研究.
对双边伤口进行个人肢体评估;不测量PAT的肢体除外.
肢体的后续分类为已愈合的伤口 (HW),未愈合的伤口 (NHW),再血管化或截肢.
接收器操作特征 (ROC) 曲线分析,以确定PAT切线的伤口愈合.

主要成果:

分析了88名患者的100个肢体 (80. 68%是男性,中位数为75岁).
验证的伤口愈合截止时间为180. 5毫秒.
结果包括26%的高血压,31%的高血压,33%的重血管化和7%的截肢.
平均PAT: 159. 81毫秒 (HW),199. 32毫秒 (NHW),239. 18毫秒 (重血管化),279. 14毫秒 (截肢).
在NHW肢体中 (61. 3%) 的PAT超过180毫秒,而在HW肢体中为19. 2% (p<0. 001,OR=6. 65).

结论:

在患有PAD的糖尿病患者中,180毫秒的PAT切断值已被验证为预测伤口愈合.
较高的PAT值与较差的结果显著相关,包括再血管和截肢.
在未愈合的伤口中,接近180毫秒的PAT值表明愈合轨迹更有利.

关键词:

糖尿病类疾病糖尿病脚脚踏加速时间周围动脉疾病伤口

更多相关视频

Demonstration of the Rat Ischemic Skin Wound Model

Demonstration of the Rat Ischemic Skin Wound Model

Published on: April 1, 2015

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

相关概念视频

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...