由瘤激活的纳米复合体将癌症和巨代谢重编程以相反的方向来克服免疫抑制

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Updated: Sep 9, 2025

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
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Published on: November 28, 2019

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Zan Dai1, Qiaoyun Wang2, Ming Zhang3

  • 1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia; Children's Cancer Institute, School of Medicine and Health, UNSW Sydney, Sydney, 2052, Australia.

Biomaterials
|August 31, 2025
PubMed
概括

这项研究引入了一种酸激活的纳米复合物,可清除硫化 (H2S),重编程癌细胞和瘤相关的巨细胞代谢,增强抗瘤免疫力并抑制瘤生长.

关键词:
癌症免疫疗法巨细胞纳米复合体瘤代谢

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