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癌症中蛋白质脂化变化:与感觉神经元功能障碍的隐藏联系

  • 0Department of Biochemistry and Molecular Biology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

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此摘要是机器生成的。

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mTOR Signaling and Cancer Progression 03:03

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Notch Signaling Pathway 03:14

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Receptor Downregulation in MVBs 01:15

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PI3K/mTOR/AKT Signaling Pathway 01:22

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The mammalian target of rapamycin  (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1  (mTORC1) and mTOR complex 2  (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast,  mTORC2 consists of a...