在左束分支区域加快后,基于压力对隔膜功能进行评估
Emine Özpak1, Thomas Van Overmeiren1, Simon Calle1
1Department of Cardiology, Ghent University Hospital, Ghent, Belgium.
Heart rhythm
|August 31, 2025
概括
对于左捆分支区域加速 (LBBAP) 的深隔膜置通常保持隔膜收缩性. 然而,特定的心电图发现可能表明植入后隔膜收缩模式异常.
科学领域:
- 心脏病学
- 电生理学
- 心脏节拍
背景情况:
- 左束支部区域加速 (LBBAP) 涉及深部隔膜植入.
- 这种深层置对隔膜收缩性的影响尚不完全理解.
研究的目的:
- 评估LBBAP中深隔膜部署对隔膜收缩和激活序列的影响.
- 评估隔膜张力的变化,并确定节奏过程中的收缩模式.
主要方法:
- 对接受LBBAP治疗的84名成年患者进行前性分析.
- 在植入前和植入后的压力成像 (GLS,PSS),内在节律和VVI节奏.
- 对隔膜张力曲线的评估和收缩模式的识别.
主要成果:
- 在基线功能正常的患者中,内在峰值 Septal Strain (PSS) 没有显著变化.
- 在LBBAP后,患者的隔膜功能显著改善.
- 在VVI激活过程中发现了四种隔膜收缩模式;较高的分数与不协调的激活和心室功能的降低相关.
- 在V1中没有终端R'波预测了隔膜收缩的失调.
结论:
- 对于LBBAP而言,深部隔膜置通常不会影响隔膜收缩性.
- 大多数患者在LBBAP后保持正常的隔膜收缩模式 (I和II).
- 在V1中缺少R'波与异常的隔膜收缩有关,可能会影响LBBAP的结果.
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