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Updated: Sep 9, 2025

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通过调节Nrf2/NF-κB/NLRP3信号通路,Piezo1促进大肠炎的进展

Pei Zhou1, Liwu Zeng1, Kai Ma1

  • 1Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022,China.

Biochemical pharmacology
|August 31, 2025
PubMed
概括

通过破坏免疫平衡和肠道屏障功能,Piezo1是一种机械敏感的离子通道,会加剧炎症性肠病 (IBD). 抑制Piezo1对小鼠的结肠炎产生保护作用.

关键词:
大肠炎在 NF-κB在NLRP3没有.皮埃佐1

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