加速计定义的体力活动和生活质量
Stephan A C Schoonvelde1, Peter-Paul Zwetsloot2,3, Alexander Hirsch2,4
1Department of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, The Netherlands s.schoonvelde@erasmusmc.nl.
Heart (British Cardiac Society)
|August 31, 2025
概括
患有缩性心肌病症 (HCM) 的患者体力活动水平低于健康人群. 增加每天的步伐与更好的生活质量相关, 强调个性化的运动指导.
科学领域:
- 心脏病学
- 运动生理学
- 遗传学
背景情况:
- 由于心脏突然死亡的担忧,心脏缩性肌肉病 (HCM) 患者通常会限制身体活动.
- 与临床因素和生活质量 (QoL) 相关的HCM体育活动的客观数据有限.
研究的目的:
- 客观地评估高性心肌病患者的体力活动模式.
- 研究HCM患者的体力活动,临床表型和生活质量 (QoL) 之间的关系.
主要方法:
- 用于测量203名HCM患者和37名基因型阳性,表型阴性 (G+/ P-) 对照的7天加速计.
- 评估每日步骤,中度至强度的体力活动 (MVPA) 和久坐.
- 使用堪萨斯城心肌病问卷 (KCCQ) 和EuroQoL5域5级 (EQ-5D-5L) 评估的质量.
主要成果:
- 与对照组相比,HCM患者的每日步伐显著减少,MVPA减少,久坐时间较高 (p<0. 01).
- 症状,阻塞性和无症状阻塞性HCM患者的活性最低;肥胖和心脏药物也与活动减少有关.
- 较高的每日步数与KCCQ和EQ-5D-5L得分的改善正相关 (p<0.001).
结论:
- 身体活动在HCM患者中客观上较低,特别是那些有症状,阻塞或肥胖的人.
- 即使是每天步骤的小幅增加也与更好的QOL有关,这强调了为HCM患者量身定制的运动建议的重要性.
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