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在体外检测N终端乙转移酶活性

Taining Li1, David C Schultz2, Ronen Marmorstein1

  • 1Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States; Abramson Family Cancer Research Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.

Methods in enzymology
|August 31, 2025
PubMed
概括

对N终端乙转移酶 (NATs) 的新测试使研究人员能够研究蛋白质乙化. 这些方法支持针对NAT活性变化的各种疾病开发NAT向疗法.

关键词:
乙-CoA合成酶短链 (ACSS)光检测高通量选 (HTS)在体外活动测定发光测试N-终端乙转移酶 (NAT)放射性检测方法

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