在关节镜肩部手术期间,炎症生物标志物预测Cutibacterium acnes在门区的检测
Kazuya Uehara1, Kiminori Yukata2, Takashi Imagama1
1Department of Orthopaedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Japan.
概括
在肩膀手术期间,中性粒细胞与淋巴细胞的比率 (NLR) 和单细胞与淋巴细胞的比率 (MLR) 的升高预示着Cutibacterium acnes (C. acnes) 的发现. 这些炎症生物标志物可以识别有风险的患者,以加强感染预防.
科学领域:
- 整形医学
- 微生物学
- 炎症发生
背景情况:
- (C. acnes) 是手术后肩部感染的常见原因.
- 在手术前确定高风险患者有助于实施有针对性的预防措施.
- 预测C. acnes在关节镜门上的检测对于预防手术部位感染至关重要.
研究的目的:
- 在关节镜手术门口预测C. 的生物标志物.
- 评估手术前炎症标志物与手术内细菌存在之间的关联.
主要方法:
- 分析了接受关节镜肩部手术的110名患者.
- 通过从关节透视门口取 swab 培养物来评估 C. acnes 的存在.
- 手术前的中性粒细胞与淋巴细胞比率 (NLR) 和单细胞与淋巴细胞比率 (MLR) 与细菌检测相关.
主要成果:
- 在18. 2%的患者中检测到C.
- 在阳性C. acnes培养的患者中观察到显著升高的NLR和MLR.
- 通过ROC分析,最佳预测值为NLR1.73和MLR0.17.
结论:
- 在手术前增加的NLR和MLR与手术内发现C. acnes有关.
- 这些炎症标志物可以识别患有细菌污染风险较高的患者.
- 这些发现支持使用NLR和MLR来增强手术前预防策略.
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