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在儿童患者接受抗吸收治疗之前,是否需要牙清洁?
Timothy W Neal1, Sayyed Mohseni1, Victoria Ratcliffe1
1Department of Surgery, Division of Oral and Maxillofacial Surgery, UT Southwestern/Parkland Memorial Hospital, Dallas, TX, USA.
Oral surgery, oral medicine, oral pathology and oral radiology
|August 31, 2025
概括
在抗吸收疗法之前接受牙清除的儿科患者没有出现与药物相关的骨缩 (MRONJ) 的风险增加. 牙清洁与更好的后续护理有关.
科学领域:
- 儿童牙科
- 口腔医学
- 药理学
背景情况:
- 与药物相关的骨 (MRONJ) 是抗吸收疗法的潜在并发症.
- 在接受抗吸收药物的儿科患者中,治疗前牙清除的作用需要研究.
研究的目的:
- 为了比较患有或没有治疗前牙清除的儿科患者的MRONJ发病率.
- 评估牙干净度对治疗后牙随访频率的影响.
主要方法:
- 用抗吸收剂治疗的儿科患者 (< 18 岁) 的回顾性研究 (2010 - 2024 年).
- 在治疗前有牙清除和没有牙清除的组之间,对MRONJ发生率和牙检查频率进行比较.
主要成果:
- 在清除 (n=88) 或无清除 (n=48) 组中没有观察到MRONJ病例.
- 与没有清除组 (0. 55) 相比,清除组在治疗后的平均每年牙科检查次数显著增加 (1. 21).
结论:
- 在接受抗吸收治疗的儿科患者中,治疗前的牙清除似乎不会增加MRONJ的风险.
- 在这一群体中,牙清除与持续的日常牙科随访有关.
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