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Updated: May 10, 2026

Generation of Human Brain Organoids for Mitochondrial Disease Modeling
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由糖酶1缺乏引起的线粒体功能障碍会扰乱人类多能干细胞的内皮和膜发育

Suji Jeong1, Hyebin Koh2,3, Minje Kang1

  • 1Department of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.

Experimental & molecular medicine
|August 31, 2025
PubMed
概括

在人类诱导的多能干细胞 (hiPS) 区分成最终的内皮细胞 (DE) 中,Gloxalase 1 (GLO1) 是至关重要的. GLO1维持线粒体平衡,对于DE和气泡发育至关重要.

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