Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

1.0K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Terminal-Group Engineering to Amplify Asymmetric Electronic Interactions in COFs for Enhanced Optoelectronic Performance.

Nano letters·2026
Same author

Structural fatigue failure analysis and lifetime reliability monitoring strategy of the lattice jib in all-terrain cranes.

Scientific reports·2026
Same author

Zero-Contrast Percutaneous Renal Denervation Guided by Multimodal Image Fusion.

JACC. Case reports·2026
Same author

Comment On "Pilot Study of Immediate Lymphatic Reconstruction (ILR) During Lymph Node Dissection for Node-Positive Melanoma: Feasibility, Safety, and Early Outcomes".

Journal of surgical oncology·2026
Same author

SOD1 lactylation impair its enzymatic activity by conformational change to aggravate intervertebral disc degeneration.

Nature communications·2026
Same author

ABSCISIC ACID-INSENSITIVE 5 (ABI5) Orchestrates Seasonal Growth Cessation and Wood Formation Inhibition in <i>Populus tomentosa</i>.

Plants (Basel, Switzerland)·2026

相关实验视频

Updated: Sep 9, 2025

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.9K

基于多乳酸的神经再生的研究进展

Qingyuan Wu1, Xiangqi Hui1, Changqing Li1

  • 1Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China.

Tissue engineering. Part B, Reviews
|September 1, 2025
PubMed
概括

聚乳酸 (PLA) 对外围神经再生具有前景,为长期神经缺陷提供解决方案. 这种可生物降解的材料可以被设计成各种形式来增强神经修复和改善患者的生活质量.

科学领域:

  • 生物材料科学
  • 神经组织工程
  • 聚合物化学

背景情况:

  • 周围神经受伤会导致显著的感觉,运动和疼痛缺陷,影响生活质量.
  • 目前治疗长隙神经缺陷的方法包括移植或导管, 这凸显了对先进生物材料的需求.
  • 聚乳酸 (PLA) 是一种具有神经组织工程潜力的多功能合成聚合物.

研究的目的:

  • 审查聚乳酸 (PLA) 的特性和合成.
  • 研究添加剂对PLA机械特性的影响.
  • 评估基于PLA的外围神经再生策略.

主要方法:

  • 聚乳酸 (PLA) 的特性,合成和修改的审查.
  • 对PLA适用于神经组织工程应用的分析.
  • 评估各种基于PLA的结构 (脚手架,管道等) 为了修复神经.

主要成果:

  • 多乳酸 (PLA) 具有有利于神经再生的机械,生物降解和生物活性特性.
  • 可以使用添加剂来定制PLA的机械性能.
  • 基于PLA的支架,导管和药物输送系统显示有促进外围神经修复的潜力.
关键词:
周围神经的再生多乳酸组织工程

更多相关视频

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration
09:17

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

Published on: February 26, 2015

21.5K
Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
05:04

Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration

Published on: May 5, 2020

7.6K

相关实验视频

Last Updated: Sep 9, 2025

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.9K
Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration
09:17

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

Published on: February 26, 2015

21.5K
Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
05:04

Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration

Published on: May 5, 2020

7.6K

结论:

  • 聚乳酸 (PLA) 和其衍生品是外围神经再生的有希望的生物材料.
  • 基于PLA的策略在神经组织工程中提供了多种应用.
  • 进一步开发PLA应用可以显著改善神经损伤的结果.