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Updated: Sep 9, 2025

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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在CD4+ T细胞中的Atg7通过调节Ets1介导的T细胞分化来改善肠粘膜炎症

Yue-Tao Zhou1, Quan-Gui Zhang1, Si-Yuan Du2

  • 1MOE Medical Basic Research Innovation Center for Gut Microbiota and Chronic Diseases, Wuxi School of Medicine, Jiangnan University, Wuxi, People's Republic of China.

Clinical and translational medicine
|September 1, 2025
PubMed
概括

CD4+ T 细胞中的自相关基因7 (Atg7) 通过抑制 Th1 细胞和通过 Ets1 促进调节性 T 细胞来降低炎症性肠病 (IBD) 的严重程度. 这突出了Atg7作为IBD的潜在治疗点.

关键词:
时间:CD4+ T 细胞美国Th1 的区分自食症

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