优化肌缩侧面硬化症患者的卡路里摄入量:复杂行为改变干预的过程评估
Katie Hullock1, Alicia O'Cathain2, Fiona Sampson2
1Sheffield Clinical Trials Research Unit (CTRU), Sheffield Centre for Health and Related Research, The University of Sheffield, Sheffield, UK.
概括
这项研究发现,在肌缩侧面硬化症 (ALS) 中优化热量摄入的新干预措施是可行的,并且具有高可靠性. 患者和护理人员发现它很有价值,尽管随着疾病的进展,可用性可能会下降.
科学领域:
- 神经学
- 临床营养
- 医疗服务研究
背景情况:
- 在保持充足的卡路里摄入量方面,
- 优化营养对于控制ALS的进展和生活质量至关重要.
- 一项新的干预措施是针对ALS患者的卡路里摄入量.
研究的目的:
- 评估ALS患者的新热量摄入优化干预措施的干预效率和用户体验.
- 在现实临床环境中评估干预的可行性和可接受性.
主要方法:
- 在英国15个ALS专家中心进行了一项随机对照试验并进行了一项混合方法的过程评估.
- 数据包括真实性检查清单 (n=146),干预会话记录以及与医疗保健专业人员 (HCP),患者和护理人员 (n=32) 的定性访谈.
主要成果:
- 观察到高干预准确度 (88%).
- 医疗人员,患者和护理人员认识到这一干预的价值,
- 患者被感知疾病减缓和控制感所激励, 尽管他们面临诸如体重增加和身体限制等挑战. 护理人员的支持对于坚持至关重要.
结论:
- 干预是可行的,并提供高准确性.
- 患者参与度很强,但由于身体功能下降,可用性可能受到限制.
- 这种干预措施可能最适合缓慢进展的ALS; 需要进一步评估有效性和子组差异.
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