术前的CONUT评分预测了治疗性胃切除的I-III期胃癌患者的术后并发症
İsmail Tırnova1, Ahmet Serdar Karaca1
1Department of General Surgery, Başkent University İstanbul Hospital, İstanbul, Türkiye.
Turkish journal of surgery
|September 1, 2025
概括
术前控制营养状况 (CONUT) 评分预测手术后胃癌患者的并发症. 高CONUT分数是胃癌切除后并发症的独立危险因素.
科学领域:
- 癌症学
- 手术胃肠病学
- 营养科学
背景情况:
- 使用血清白蛋白,总胆固醇和淋巴细胞计数的控制营养状况 (CONUT) 评分被认为可以预测胃肠癌手术后的并发症.
- 经过胃切除术的胃癌患者面临术后并发症的风险.
研究的目的:
- 在经过胃切除术的I-III期胃癌患者中,评估术前CONUT评分对整体术后并发症 (OPC) 的预测值.
主要方法:
- 在2013年1月至2024年12月间接受治疗性胃切除术的GC患者的回顾性分析.
- 患者分为正常 (CONUT分数0- 1) 和高 (CONUT分数≥2) 的手术前CONUT组.
- 进行单变量和多变量分析以确定OPC的风险因素.
主要成果:
- 高CONUT组的患者表现出显著更高的麻醉学会得分,中性粒细胞/淋巴细胞比率,淋巴侵袭率,TNM阶段,ICU停留时间,OPC率和综合并发症指数.
- 多变量分析确定了晚期TNM阶段 (OR: 5. 8, 95% CI: 1. 4 - 24. 6, p=0. 016) 和高CONUT分数 (OR: 4. 1, 95% CI: 1. 3 - 13. 0, p=0. 014) 作为PC的独立风险因素.
结论:
- 在为胃癌进行治疗性胃切除术的患者中,手术前的CONUT分数是整体术后并发症的潜在预测指标.
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