电脑电图录制的时间是否会影响其预测进一步的发作?
Tal Gilboa1,2, Ella Rochberg Hanuka3, Tzlil Y Shifman4
1Child Neurology Unit, Hadassah Medical Organization, Jerusalem, Israel.
European journal of neurology
|September 1, 2025
概括
在第一次无缘性发作 (FUS) 之后,脑电图 (EEG) 有助于预测未来的发作. 晚期脑电图显示型活动是儿童复发的强烈预测因素.
科学领域:
- 神经学
- 临床神经生理学
背景情况:
- 不正常的脑电图 (EEG) 是第一个未引起的发作 (FUS) 后发作复发的已知危险因素.
- 在儿童和成人群体中,早期对晚期脑电图的预测价值尚未完全阐明.
研究的目的:
- 评估早期 (在2天内) 和晚期脑电图 (EEG) 的预测价值,用于儿童和成年患者在第一次未引起的发作 (FUS) 后的随后的发作.
主要方法:
- 在2011年4月至2015年12月期间,对202名患者 (137名儿童,65名成年人) 进行了脑电图.
- 脑电图被分类为一般异常或特异性形,并被分类为早期或晚期,与患者人口统计学,抗发作药物 (ASM) 使用和两年内发作复发相关.
主要成果:
- 与成年人相比,儿童早期和晚期脑电图显示出更多异常. 晚期脑电图 (OR 3. 085, p=0. 006) 和抗发作药物 (ASM) 的使用 (OR 0. 39, p=0. 018) 显著与多变量分析中的额外发作有关.
- 这些关联在儿科患者中尤为突出,突出了晚期EEG发现的预后价值和ASM对复发的潜在影响.
结论:
- 在FUS之后,早期和晚期的EEG具有明显的临床效用.
- 早期的脑电图对于初始诊断有价值,而晚期的脑电图则为复发提供了更好的预后信息.
- 建议在更大规模的前性研究中进一步验证这些发现.
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