2014-2022年爱尔兰初级保健中止痛药处方和高风险处方模式 - 一项重复的横截面研究
Molly Mattsson1, Ahmed Hassan Ali1, Fiona Boland2
1School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
European journal of pain (London, England)
|September 1, 2025
概括
爱尔兰的止痛药使用总体下降,主要是由于非类固醇抗炎药物 (NSAID) 的处方减少. 然而,高风险的处方模式仍然存在,表明需要进行干预和改善专业支持.
科学领域:
- 药物监督和药物安全
- 主要护理医学
- 医疗服务研究
背景情况:
- 疼痛管理是一个重大的公共卫生挑战, 止痛药提供好处但带有风险.
- 由于潜在的副作用和依赖性,非类固醇抗炎药物 (NSAID) 和阿片类药物是高风险的止痛药.
- 了解止痛药处方趋势对于优化患者安全和医疗资源分配至关重要.
研究的目的:
- 分析2014年至2022年期间爱尔兰初级保健中止痛药处方模式的变化.
- 识别特定止痛药类的使用变化和高风险的处方行为.
- 为改善治疗疼痛的药物安全性制定策略.
主要方法:
- 使用来自爱尔兰一般医疗服务 (GMS) 计划的月度数据,用于初级保健中处方和发放的药物.
- 量化每年患病率,开始,停止和长期使用止痛药.
- 根据苏格兰多药学指南的标准进行高风险处方评估.
主要成果:
- 总体而言,止痛药的使用率从2014年的48.3%略有下降到2022年的46.3%.
- 在研究期间,非类固醇抗炎药物 (NSAID) 的使用率从29. 4%大幅下降至25. 0%.
- 其他止痛药的患病率有所增加,在2022年, gabapentinoids 和 amitriptyline 的调整率更高. 高风险的处方,如NSAID与抗凝剂,增加.
结论:
- 在爱尔兰观察到整体止痛药的使用减少,主要是由于全身NSAID处方减少.
- 其他止痛药的使用率增加可能归因于人口变化,特别是人口老龄化.
- 建议针对高风险处方和增强非药物疼痛管理服务的干预措施.
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