优化饮用水测试:评估缩短方案的可重复性和有效性:随机前性试验
Tal Yahalomi1, Hamza Rayan2, Natalya Kovalyuk2
1Department of Ophthalmology, Faculty of Health Sciences, Samson Assuta Ashdod Hospital, Ben-Gurion University of the Negev, Ashdod, Israel. yatal25@gmail.com.
International ophthalmology
|September 1, 2025
概括
缩短30分钟的饮用水测试 (WDT) 是测量眼内压力 (IOP) 波动的可靠方法. 身体质量指数 (BMI) 和身体表面积 (BSA) 在WDT中没有显著的影响.
科学领域:
- 眼科 眼科
- 大眼的研究
- 诊断测试验证
背景情况:
- 标准饮用水试验 (WDT) 评估60分钟内眼内压力 (IOP) 的波动.
- 优化诊断方案对于有效的临床实践至关重要.
- 患者的特征如BMI和BSA可能会影响内血压的动态.
研究的目的:
- 评估一个缩短30分钟的饮用水试验 (WDT) 协议.
- 评估30分钟和60分钟WDT IOP反应之间的相关性.
- 调查身体质量指数 (BMI) 和身体表面积 (BSA) 在WDT期间对内压动态的影响.
主要方法:
- 对10毫升/千克和800毫升WDT剂量方案进行前性随机研究.
- 将患者随机分配到两种WDT剂量组之一.
- 将30分钟内血压反应与60分钟内血压反应进行比较,并进行BMI和BSA分析.
主要成果:
- 在30分钟和60分钟的WDT之间观察到高可重复性 (r=0. 89, p<0. 001).
- 在WDT组之间没有发现人口,系统或眼部特征的显著差异.
- 在BMI (r=0. 12) 和BSA (r=0. 16) 和内压反应之间发现了弱相关性.
结论:
- 30分钟的WDT是一种可重复和可靠的替代方案,用于评估内压波动.
- 根据BMI或BSA调整WDT结果可能是不必要的,因为相关性很弱.
- 缩短的WDT提供了临床IOP评估的实用进展.
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