缺食症和慢性病的流行:一个横截面研究
Masahiro Egawa1, Ryuichi Yoshimura2, Kosuke Matsui1
1Division of Nephrology, Izumo Medical Life Cooperative Izumo-Shimin Hospital, Izumo, Japan.
International urology and nephrology
|September 1, 2025
概括
消化不良或吞困难与老年人慢性病 (CKD) 的更高患病率有关. 随着消化不良的严重程度的增加,这种关联变得更加明显,突出显示了潜在的临床联系.
科学领域:
- 老年学
- 肝脏病学
- 胃肠病学
背景情况:
- 全球人口老龄化,导致慢性病的发病率增加.
- 缺食症对老年人来说是一个重大的健康挑战.
- 关于食障碍与CKD患病率之间的关系的研究有限.
研究的目的:
- 在老年患者中研究食障碍与慢性病 (CKD) 患病率之间的关联.
- 要确定这种关联是否取决于食欲障碍的严重程度.
主要方法:
- 一项涉及520名65岁及以上患者的回顾性截面研究.
- 使用修改的吞水测试来评估消化不良 (得分为1-3表示消化不良).
- 通过估计的球过率 (eGFR) ≤60 mL/分钟/1.73 m2来定义CKD;用于分析的是逻辑回归.
主要成果:
- 与正常消 (38. 0%) 患者相比,慢性病的患病率更高 (62. 2%).
- 缺食症与慢性脏病发病率独立相关 (aOR为2. 51; 95% CI为1. 01- 6. 20).
- 一个显著的趋势显示了慢性脏病的患病率增加,食障碍的严重程度更高 (趋势的p=0. 044).
结论:
- 在老年人中,淋巴失调与慢性病的患病率较高有关.
- 消化不良和慢性病之间的关联取决于严重程度.
- 这些发现表明老年人的吞困难与功能下降之间存在潜在联系.
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