动脉静脉形外科手术后可逆胀:输入和输出不平衡
Daniel Sconzo1, Felipe Ramirez-Velandia1, Alejandro Enriquez-Marulanda1
1Division of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, USA.
概括
在脑动脉静脉形 (AVM) 的立体射线手术 (SRS) 后,辐射诱导的胀与更大的静脉排水变化有关. 这表明静脉外流阻力增加有助于AVM患者的SRS后.
科学领域:
- 神经学
- 放射学
- 血管外科
背景情况:
- 大脑动脉静脉形 (AVM) 是一种复杂的血管病变.
- 立体射线手术 (SRS) 是一种治疗AVM的选择.
- 辐射引起的是SRS的潜在并发症.
研究的目的:
- 在SRS进行AVM后,研究动脉输送器和静脉排水器的血管改造.
- 探索血管重塑与辐射引起的胀之间的关系.
- 在AVM患者中确定后SRS胀的预测因素.
主要方法:
- 用CyberKnifeSRS治疗的50名脑动脉瘤患者的回顾性分析.
- 单变分析以比较患有SRS后和没有SRS后的患者之间的血管改造参数.
- 评估动脉输送器和排水静脉的直径和阻力变化.
主要成果:
- 46% 的患者出现后SRS .
- edem 与更大的AVM体积和更大的静脉径减少有关.
- 患有的患者表现出更高的抵抗力,而没有的患者则表现出更高的抵抗力.
- 没有观察到辐射剂量,消灭率或功能结果的显著差异.
结论:
- 与动脉输送患者相比,AVM患者的SRS后与排泄静脉大小的不成比例减少有关.
- 排泄静脉对外流的抵抗增加可能会导致辐射诱导的胀.
- 血管改造模式可以帮助预测SRS后AVM的胀.
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