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Improving Translational Accuracy

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...

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Outcomes of 544 Patients with t(6;9)/DEK::NUP214 acute myeloid leukemia undergoing allogeneic stem cell transplantation: an EBMT study on behalf of the acute leukemia working party (ALWP) and the pediatric diseases working party (PDWP).

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Updated: Sep 9, 2025

Three-Dimensional Preoperative Virtual Planning in Derotational Proximal Femoral Osteotomy

Three-Dimensional Preoperative Virtual Planning in Derotational Proximal Femoral Osteotomy

Published on: February 17, 2023

通过数据预处理提高骨科模型 (包括机器学习) 的稳定性和可解释性

Baptiste Boukebous¹, Jacques-Emmanuel Galimard², David Biau³

¹AP-HP - Orthopédie et Traumatologie, Hôpital Beaujon 100 Bd du Général Leclerc, Clichy 92110, France; Université Paris Cité, Paris, France.

Orthopaedics & traumatology, surgery & research : OTSR

|September 1, 2025

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No abstract available in PubMed .

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Last Updated: Sep 9, 2025

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