冠状肉瘤的质子束疗法:一个系统的叙述性审查和元分析
Meng Dong1, Weidong Bao1, Dandan Wang2
1Department of Interventional Oncology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, 610036, China.
Critical reviews in oncology/hematology
|September 1, 2025
概括
质子束疗法在治疗软骨肉瘤方面表现出卓越的疗效,实现了高的局部控制和整体生存率. 这种疗法是安全且有前途的选择,
科学领域:
- 癌症学
- 辐射瘤学
- 医学物理
背景情况:
- 软骨瘤是一种罕见的骨瘤,需要有效的治疗策略.
- 评估像质子束疗法这样的新疗法对于改善患者的结果至关重要.
研究的目的:
- 系统地评估质子束疗法 (PBT) 的疗效和安全性.
- 整合现有研究的发现,以提供PBT结果的全面概述.
主要方法:
- 在PubMed,Cochrane Library和Embase数据库中进行了系统的文献搜索.
- 六项研究涉及282名接受PBT治疗的肌肉肉瘤患者.
- 使用STATA版本14.0进行统计分析.
主要成果:
- 观察到高局部控制率,在多个时间点达到100%.
- 患者的整体存活率很好,10年后的存活率为100%.
- 与治疗相关的毒性主要是低级 (≤2).
结论:
- 质子束治疗是一种有效和安全的治疗方法,包括不可手术的病例.
- 治疗显示出有利的局部控制和整体存活率,毒性概况可控.
- PBT是治疗冠状腺癌患者的一个有前途的选择.
相关概念视频
02:57Targeted Cancer Therapies
7.8K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.8K
02:49Cancer Therapies
7.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.9K