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Updated: Sep 9, 2025

Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers
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针对IP6包装缺陷的HIV-1囊的结构基础

Yanan Zhu1,2, Alex B Kleinpeter3, Juan S Rey4

  • 1Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

Nature communications
|September 1, 2025
PubMed
概括

在IP6缺乏的病毒中,HIV-1囊蛋白的新突变 (G225R) 通过稳定Gag格子来恢复感染力. 这一发现揭示了体C端在病毒组合和适应中的关键作用.

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