在永久居住在高原地区的未经治疗的高血压个体中研究出门式血压表型及其与血红蛋白度的相关性
在PubMed上查看摘要
概括
此摘要是机器生成的。高海拔高血压通常是持续的,夜间高血压是关键的表型. 在这些患者中,较低的血红蛋白水平 (< 16 g/ dL) 与较高的夜间缩血压和较低的夜间血压下降相关.
科学领域
- 心血管研究
- 高空医学
- 高血压研究
背景情况
- 对于高空高血压患者的门诊血压监测 (ABPM) 数据很少.
- 了解高血压表型及其与血红蛋白的关联对于这一群体至关重要.
- 在高海拔地区生活的未经治疗的高血压患者是一个独特的研究群体.
研究的目的
- 使用ABPM在未经治疗的高海拔高血压患者中探索高血压表型.
- 调查血红蛋白水平与夜间血压指数之间的联系.
- 在这个群体中确定血红蛋白对血压的影响的潜在值.
主要方法
- 在高海拔地区招募342名未经治疗的高血压患者.
- 使用门诊血压监测 (ABPM) 来评估高血压表型.
- 分析了血红蛋白水平与夜间静脉压 (SBP) 和夜间静脉压下降之间的相关性.
主要成果
- 持续高血压 (SH) 是普遍存在的 (91. 80%),昼夜高血压是主要的表型 (94. 26%).
- 与血红蛋白≥16g/ dL患者相比,血红蛋白<16g/ dL患者的夜间平均血压较高,夜间血压下降的比例较高 (<10%).
- 血红蛋白与夜间平均SBP有显著的反相关性,与夜间SBP下降有正相关性,特别是在血红蛋白< 16g/ dL的个体中.
结论
- 夜间高血压是高海拔高血压患者中普遍存在的ABPM表型.
- 在这一群体中,较低的血红蛋白水平 (< 16 g/ dL) 与不良的夜间血压模式显著相关.
- 在高海拔高血压患者的夜间血压评估中,需要考虑血红蛋白度.
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