Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Tissue Transplantation01:24

Tissue Transplantation

519
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
519
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

60
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
60
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

493
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
493

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Cardio amyloid-artificial intelligence: advanced multi-modal screening for transthyretin cardiac amyloidosis in severe aortic stenosis patients.

European heart journal. Digital health·2026
Same author

An artificial intelligence model to detect abnormal ejection fraction from non-contrast chest computed tomography: the CT-LVEF study.

European heart journal. Digital health·2026
Same author

The novelty of anticoagulation in LVAD Therapy: Current Practice, the Role of Direct Oral Anticoagulants, and Future Directions.

Journal of cardiovascular pharmacology·2026
Same author

A two-threshold donor-derived cell-free DNA algorithm improves detection of molecular rejection in heart transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

De Novo Aortic Insufficiency and Its Progression in Patients on Microaxial Flow Pump Support Before Durable Left Ventricular Assist Device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

The Pendulum Swings: Reconsidering Durable Left Ventricular Assist Devices as a Bridge to Transplantation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

相关实验视频

Updated: Sep 9, 2025

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
06:40

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

261

血液循环死亡心脏移植后捐赠者与接受者的性别不匹配的影响

Kavya Rajesh1, Iris Feng1, Farhana Latif2

  • 1Division of Cardiothoracic and Vascular Surgery, New York Presbyterian Hospital, Columbia University Medical Center, New York, New York, USA.

Clinical transplantation
|September 2, 2025
PubMed
概括

在循环死亡 (DCD) 后接受心脏移植的女性面临更高的急性排斥率. 捐赠者/接受者的性别不匹配影响了DCD心脏移植的结果,但所有接受者的长期存活率都相似.

关键词:
联合国工作人员数据库在循环死亡后的捐赠心脏移植性别不匹配

更多相关视频

Optimization of the Cuff Technique for Murine Heart Transplantation
14:01

Optimization of the Cuff Technique for Murine Heart Transplantation

Published on: June 26, 2020

9.4K
A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia
12:40

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia

Published on: September 28, 2022

1.8K

相关实验视频

Last Updated: Sep 9, 2025

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
06:40

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

261
Optimization of the Cuff Technique for Murine Heart Transplantation
14:01

Optimization of the Cuff Technique for Murine Heart Transplantation

Published on: June 26, 2020

9.4K
A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia
12:40

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia

Published on: September 28, 2022

1.8K

科学领域:

  • 心脏病学
  • 移植免疫学
  • 器官捐赠

背景情况:

  • 之前的研究表明,捐赠者与接受者的性别不匹配会在脑死亡 (DBD) 心脏移植后恶化捐赠结果.
  • 性别不匹配对循环死亡 (DCD) 心脏移植后捐献的影响仍然不太清楚.

研究的目的:

  • 调查捐赠者/接受者的性别不匹配对DCD心脏移植结果的影响.
  • 确定与急性排斥和手术后并发症相关的因素.

主要方法:

  • 来自UNOS数据集的1260例DCD心脏移植的分析 (12/2019-12/2023).
  • 分为四个性别匹配组:FD/FR,FD/MR,MD/MR,MD/FR.
  • 主要结局:急性排斥,术后并发症. 二次结果:死亡率.
  • 使用多变量逻辑回归和卡普兰-梅尔生存分析.

主要成果:

  • 与男性接受者相比,女性接受者呈现的急性排斥率显著更高 (20-22. 2% vs 9-11. 8%,p=0. 001).
  • 接受者的体重,身高和LVAD使用与男性接受者的急性排斥有关,而不是女性接受者.
  • 在手术后并发症 (中风,透析,心脏起器) 或长期死亡率方面没有观察到显著差异.

结论:

  • 与男性接受者相比,接受DCD心脏的女性患急性排斥的风险增加.
  • 接受者人体测量影响了男性DCD心脏接受者的急性排斥风险.
  • 捐赠者/接受者的性别不会影响DCD心脏移植后的长期存活.