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Updated: Sep 9, 2025

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对人类前性痴呆神经元中纠正tau介导病理的新型小分子的表型屏幕

Hannah Maxwell1, James Smith1, Tom Campbell1

  • 1Talisman Therapeutics, Babraham Research Campus, Cambridge, UK.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|September 2, 2025
PubMed
概括

研究人员对成千上万种化合物进行了选, 寻找能够修复前性痴呆神经元中核膜缺陷的药物. 通过改变微管和tau水平来纠正tau病理的几个有前途的分子被确定.

关键词:
前性痴呆症人类诱导的多能干细胞微管子核包裹现型屏幕病症

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