患有PTSD的女性非情绪性工作记忆能力下降:与症状相关
Natsuki Ueda1,2, Mingming Lin1,3, Mariko Itoh1,4
1Department of Behavioral Medicine, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
European journal of psychotraumatology
|September 2, 2025
概括
患有创伤后应激障碍 (PTSD) 的个人表现出非情感工作记忆 (WM) 能力受损,特别是在复杂的任务中. 这种认知缺陷与更严重的PTSD症状有关,
科学领域:
- 神经科学
- 心理学
- 认知科学
背景情况:
- 创伤后应激障碍与工作记忆 (WM) 缺陷有关.
- 之前对非情绪性脑震荡的研究已经产生了不一致的结果.
研究的目的:
- 使用N-back任务调查PTSD与非情绪工作记忆 (WM) 之间的关系.
- 为了澄清患有PTSD的人的认知缺陷.
主要方法:
- 有111名患有PTSD的女性和120名健康对照人完成了非情绪刺激的0背和2背任务.
- 参与者还接受了神经心理测试,并填写了创伤后应激障碍和抑郁症问卷.
- 这项研究集中在一个平民样本, 许多与人际暴力相关的PTSD.
主要成果:
- 与对照组相比,PTSD组在双背任务上的准确性明显较低.
- 两组之间没有发现0-back任务准确度的显著差异.
- 在0背和2背任务中, PTSD组表现出延长的反应时间.
- 在PTSD组中,较慢的双回反应时间与整体和避免症状的严重程度相关.
结论:
- 患有PTSD的个人表现出工作记忆 (WM) 能力的下降.
- 这项研究提供了WM缺陷的证据,
- 在PTSD中WM功能障碍可能与特定的症状特征有关,特别是回避行为.
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