高强度间歇训练和正念呼吸诱导肥胖的绝经后妇女的荷尔蒙,代谢和抗癌作用:随机对照试验
Ebtesam N Nagy1, Marwa Shafiek2, Hend Elsheimy3
1Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Dokki, Giza, Egypt.
Journal of evidence-based integrative medicine
|September 2, 2025
概括
高强度间歇训练 (HIIT) 和正念呼吸显著改善了肥胖的绝经后妇女的代谢,激素和瘤风险因素. 这些干预措施有效地降低了体重,胰岛素抵抗和关键生物标志物.
科学领域:
- 内分泌学
- 代谢健康
- 癌症学
背景情况:
- 肥胖和更年期后与代谢,荷尔蒙和瘤相关的风险增加有关.
- 在绝经后的妇女中,生活方式干预对于控制这些风险至关重要.
研究的目的:
- 研究高强度间歇训练 (HIIT) 和正念呼吸对性激素,胰岛素抵抗,脂质样本和瘤生物标志物的影响.
- 在肥胖的绝经后妇女中评估HIIT和正念呼吸的有效性.
主要方法:
- 一项为期12周的前性随机受控研究,涉及70名肥胖的绝经后妇女 (年龄在55-65岁之间,BMI在35- 44. 9公斤/ m2).
- 参与者被分配到实验组 (HIIT+正念呼吸+药物治疗) 或对照组 (仅药物治疗).
- 评估包括血清性激素 (雌激素,,SHBG),HOMA- IR,脂质样本 (TC,TG,HDL) 和瘤标志物 (CEA,CA125).
主要成果:
- 在HIIT和正念呼吸组显示体重,BMI,自由,总,雌激素,HOMA-IR,CEA,CA125,总胆固醇,甘油三和TC/HDL比率显著降低.
- 这一组还显示性激素结合球蛋白和高密度脂蛋白的显著增加.
- 对照组的这些参数出现了不良变化,体重,BMI,荷尔蒙,胰岛素抵抗,瘤标志物和脂质增加,SHBG和HDL减少.
结论:
- 联合HIIT和正念呼吸是减轻肥胖的绝经后女性代谢,荷尔蒙和瘤相关风险因素的有效策略.
- 这些干预措施提供了一种有前途的非药物治疗方法来改善这一群体的健康状况.
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