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身体症状和相关疾病和轻度创伤性脑损伤:系统性审查

Kaiden Jobin, Alison Janelle Wilson, Regan King

Biopsychosocial science and medicine

|September 2, 2025

概括

这一系统性审查发现了有关体征和相关疾病 (SSRD) 与轻度创伤性脑损伤 (mTBI) 的证据. 然而,需要更多高质量的研究来证实SSRD和mTBI之间的关联.

科学领域:

神经学
精神病学
康复医学

背景情况:

身体症状和相关疾病 (SSRD) 是一种复杂的疾病,其特点是身体症状带来的痛苦和损伤.
轻度创伤性脑损伤 (mTBI) 可以导致广泛的急性和持续性症状,包括体质问题.

研究的目的:

对SSRD与mTBI之间的关系进行全面的系统审查.
综合现有关于这两种疾病之间关联的证据.

主要方法:

在多个数据库 (Ovid MEDLINE,Cochrane,CINAHL,SPORTDiscus,PsycINFO,Embase,Scopus) 进行了系统的搜索,直到2024年3月7日.
纳入标准集中在评估mTBI与SSRD或体化之间的相关性的人类研究上,这些研究发表在同行评审期刊上.
使用苏格兰大学间指南网络 (SIGN) 标准进行了偏差风险评估.

主要成果:

在6009个独特标题中,包括43项研究.
九项研究报告了功能性和mTBI史之间的关联.
三十一项研究研究了SSRD负担问卷和mTBI之间的关系,而三项研究则研究了医疗保健从业者对SSRD后的诊断.
其中很大一部分研究 (36/43) 具有不可接受的偏差风险;只有4项高质量,3项可接受.

结论:

大多数可接受的证据表明SSRD和mTBI之间存在关联.
然而,由于缺乏高质量的研究,证据的整体质量有限.
需要进一步的严格研究才能确定mTBI与SSRD的联系.

关键词:

简体形式大脑震荡功能性神经疾病轻度创伤性脑损伤精神性非发作身体症状障碍有机化

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