利用医疗保险索赔数据来补充疾病控制和预防中心对出生缺陷的监测系统
Sharon Ng1, Jeremy P Brown1, Loreen Straub2
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Birth defects research
|September 2, 2025
概括
医疗保险索赔数据显示出生缺陷的患病率越来越高,特别是心脏和中枢神经系统缺陷. 这种监测补充了现有的系统,有助于识别趋势和潜在的致病信号,以便进一步调查.
科学领域:
- 公共卫生监测
- 生殖健康
- 儿童流行病学
背景情况:
- 美国现有的出生缺陷监测系统收集的数据有限.
- 医疗保险索赔数据为国家趋势分析提供了补充资源.
- 索赔数据可以帮助调查潜在的致病信号和集群.
研究的目的:
- 使用医疗保险索赔数据描述国家出生缺陷流行趋势.
- 调查出生缺陷的信号,并确定随着时间的推移而发生的变化.
- 评估索赔数据在补充现有监测中的有用性.
主要方法:
- 使用Merative MarketScan商业索赔和遭遇数据库 (2016-2022年).
- 识别活生生的婴儿并将其与母亲的健康记录联系起来.
- 在生命的前三个月内使用ICD-10-CM代码定义的出生缺陷;计算的患病率估计.
主要成果:
- 分析了943,855名活生生的婴儿.
- 在2016年至2022年期间观察到心脏,中枢神经系统,耳朵,生殖器,尿道,肌肉骨和四肢缺陷的患病率增加.
- 染色体,口腔裂,呼吸道,胃肠道,血管和眼睛缺陷的稳定患病率;鉴定了结,唇,腹和阴茎形的具体趋势.
结论:
- 医疗保健索赔数据库有效地补充了传统的监控系统.
- 索赔数据可以产生,证实或反驳公共卫生信号.
- 索赔数据中的患者信息有助于对出生缺陷病因进行更深入的调查.
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