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Updated: Sep 9, 2025

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使用基于胆的深溶解剂对功能组对药物溶解性的影响

Prathiksha Prabhakar1, Anantharaj Ramalingam2

  • 1Department of Chemical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Rajiv Gandhi Salai (OMR), Kalavakkam, Chennai, Tamil Nadu, 603110, India.

Journal of molecular modeling
|September 2, 2025
PubMed
概括

深度溶解剂 (DES) 显示为可溶性较低的药物的可溶性. 胆化物 (ChCl) 与特定的键供体相结合,通过利用分子相互作用有效地提高了药物的溶解性.

关键词:
在COSMO-RS模型中胆化物功能组西格玛潜力西格玛概况不溶于水的药物

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