根据种族和种族分类的乳腺大细胞淋巴瘤
Dylan K Kim1, Lauren S Lowe1, Alfred I Neugut2,3,4
1Division of Plastic and Reconstructive Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons, Columbia University, New York, New York.
乳房植入物相关的大细胞淋巴瘤 (ALCL) 的发病率正在上升,特别是在白人和西班牙裔女性中. 从2000年至2020年间的病率显著增加,其他种族的病例较少.
科学领域:
- 癌症学
- 流行病学
- 公共卫生
背景情况:
- 与乳房植入物相关的形大细胞淋巴瘤 (ALCL) 是一种罕见但日益严重的并发症.
- 美国乳腺ALCL的种族和民族流行病学现有数据有限.
- 在全球范围内观察到ALCL发病率的地理差异.
研究的目的:
- 分析美国乳腺ALCL的发病率,按种族和民族分层.
- 在不同的人口群体中识别乳腺ALCL发病率的趋势.
主要方法:
- 基于人口的回顾性观察性队列研究.
- 使用了监测,流行病学和最终结果 (SEER) 计划 (2000-2020) 的数据.
- 包括诊断为原发性乳腺ALCL的妇女,并对T细胞淋巴瘤进行敏感性分析,未另行说明.
主要成果:
- 乳腺ALCL的总发病率为每1亿人/ 年9. 7.
- 白人 (11.6) 和西班牙裔 (7.5) 妇女的发病率最高.
- 白人和西班牙裔患者的患病率在2000-2010年至2011-2020年间显著增加,而黑人患者则没有.
结论:
- 乳腺ALCL的发病率在白人和西班牙裔人口中最高,而且增长最快.
- 需要进一步的研究来了解导致这些种族和种族差异的因素.
- 建议持续监测纹理乳房植入物的使用情况.
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