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Updated: Sep 9, 2025

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice
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A20的线性泛素结合基因抑制了Th17细胞的致病激活和IL-22驱动的肠炎

Christopher J Bowman1,2, Dorothea M Stibor1, Xiaofei Sun1

  • 1Department of Medicine.

The Journal of clinical investigation
|September 2, 2025
PubMed
概括

蛋白质A20调节T辅助细胞17 (Th17) 的扩张和IL-22 (IL-22) 的产生,这对于预防肠炎至关重要. 在A20突变导致IL-22驱动的肠炎症.

关键词:
适应性免疫胃肠病学免疫学炎症性肠道疾病

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