Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

332
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
332

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Nickel-Catalyzed Deoxyvinylation of Benzyl Alcohols via Cross-Electrophile Coupling with Vinyl Bromides.

Organic letters·2026
Same author

Honokiol attenuates neuroinflammation and enhances remyelination in mouse models of multiple sclerosis through PPARγ-mediated ERK/AKT signalling.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same author

Sex Disparities in Atrial Fibrillation and Atrial Flutter Presentation, Treatment, and Outcomes in Reproductive-Aged Individuals.

Journal of cardiovascular electrophysiology·2026
Same author

Precise microfluidic engineering of mRNA lipid nanoparticle-loaded polycaprolactone microcapsules for sustained delivery.

Journal of materials chemistry. B·2026
Same author

Pan-TRK expression and NTRK gene aberrations in meningiomas: association with tumor grade and proliferative activity.

The journal of pathology. Clinical research·2026
Same author

Cpumycins A-C, Aminated Benzoic Dimers from <i>Streptomyces</i> sp. CPU-W6, and Their Potential Cardioprotective Activities.

Journal of natural products·2026

相关实验视频

Updated: Sep 9, 2025

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
09:35

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

511

在急性心肌梗塞患者中,血红蛋白糖化指数与28天全因死亡率之间的关联:MIMIC- IV数据库的分析

Yue Lv1, Lingchen Wei1, Ziyue Wang1

  • 1College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.

PloS one
|September 2, 2025
PubMed
概括

血红蛋白糖化指数 (HGI) 可以预测急性心肌梗塞 (AMI) 患者的短期死亡率. 在重症监护室患者中,低HGI水平与28天死亡率的增加有着令人惊的联系.

更多相关视频

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

370
A Modified Simple Method for Induction of Myocardial Infarction in Mice
04:29

A Modified Simple Method for Induction of Myocardial Infarction in Mice

Published on: December 3, 2021

3.8K

相关实验视频

Last Updated: Sep 9, 2025

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
09:35

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

511
Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

370
A Modified Simple Method for Induction of Myocardial Infarction in Mice
04:29

A Modified Simple Method for Induction of Myocardial Infarction in Mice

Published on: December 3, 2021

3.8K

科学领域:

  • 心脏病学
  • 代谢综合征
  • 临床研究

背景情况:

  • 急性心肌梗塞 (AMI) 是全球死亡的主要原因.
  • 血红蛋白糖化指数 (HGI) 与不良健康结果有关,但其在短期AMI预后中的作用尚不清楚.

研究的目的:

  • 在首次AMI患者中研究HGI与短期死亡率之间的关联.
  • 评估HGI作为一种潜在的预测性生物标志物,用于AMI后的不良结果.

主要方法:

  • 来自MIMIC- IV 3.1数据库的1008名第一次ICU AMI患者的数据分析.
  • 使用禁食血葡萄糖 (FPG) 和糖化血红蛋白 (HbA1c) 计算HGI.
  • 卡普兰-梅尔生存分析,考克斯比例危险模型,受限立方线分析和机器学习模型 (Boruta,SHAP).

主要成果:

  • 最低HGI四分位数 (Q1) 患者的28天ICU和住院死亡率显著上升.
  • 在HGI和死亡率之间观察到U形关联,低HGI是不良结果的强有力的预测因素.
  • 机器学习模型证实了HGI对AMI短期不良事件的预测能力.

结论:

  • 血红蛋白糖化指数 (HGI) 是急性心肌梗塞患者短期死亡的重要和独立预测指标.
  • 与预期相反,低HGI水平与AMI后死亡风险增加有关.
  • 在AMI患者中,HGI可作为一种有价值的临床生物标志物.