在使用吸入性皮质类固醇的肺结核患者中进行系统查的效果
Manju Rajaram1, Palanivel Chinnakali2, Vinayagamoorthy Venugopal3
1Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Lung India : official organ of Indian Chest Society
|September 2, 2025
概括
使用高剂量的吸入性皮质类固醇的患者和糖尿病患者患结核的风险增加. 建议针对这些人进行查,以便及早发现结核病.
科学领域:
- 肺部医学
- 传染性疾病
- 药理学
背景情况:
- 吸入性皮质类固醇 (ICS) 与结核病 (TB) 的风险增加有关.
- 在ICS使用者中发展结核病的特定危险因素需要进一步调查.
研究的目的:
- 在使用吸入性皮质类固醇的患者中识别结核病的危险因素.
- 为此群体提供针对性肺结核查策略.
主要方法:
- 在印度普杜切里进行的横截面研究.
- 包括1550名在ICS治疗一年多的患者,他们可能有结核病症状.
- 诊断方法包括唾液涂抹,胸部放射,CBNAAT,支气管和BAL用于微生物学确认.
主要成果:
- 糖尿病和较高剂量的ICS是结核病的独立危险因素 (分别为6. 4和7).
- 其他确定的危险因素包括男性性别,冠状动脉疾病,吸烟和酒精使用.
- 需要对262名患者进行查,以确定一个结核病例.
结论:
- 糖尿病患者和高剂量药物治疗患者需要针对性结核查.
- 通过查及早检测对于对弱势群体的结核病管理至关重要.
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