与住院时间和死亡率增加相关的持续性精神错乱
Jerry Bradley1, Fei Tang2, Zachary Panzarella3
1Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
PloS one
|September 2, 2025
概括
持续的妄想会显著增加住院老年人的死亡风险. 每增加一天的妄想都与死亡风险增加有关,
科学领域:
- 老年医学
- 危急护理医学
- 流行病学
背景情况:
- 妄是一种已知的住院后死亡风险因素.
- 持续性妄想对长期死亡率的具体影响尚不清楚.
研究的目的:
- 在65岁以上的住院患者中调查持续的妄想和死亡率之间的联系.
- 量化与不同持续时间的妄想相关的死亡风险.
主要方法:
- 在4560名65岁以上的患者中进行了回顾性队列研究.
- 使用护士 Delirium 查量 (NuDESC) 评分 (≥2) 发现的 Delirium.
- 多变量逻辑回归分析了30,60,90,180和360天的死亡率,并对共变量进行了调整.
主要成果:
- 13. 9% 的患者出现了妄想.
- 持续的妄想与30天死亡率的增加密切相关 (例如,4天: aOR 7. 21).
- 在所有随访期间,每增加一天的妄想,死亡风险都逐渐增加.
结论:
- 持续的妄想是老年人住院死亡率的重要预测因素.
- 死亡的风险随着妄的持续时间而升级.
- 早期识别和治疗持续的妄想是非常重要的.
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