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Updated: Sep 9, 2025

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
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Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

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条件疼痛调节的个体差异与α振荡有关

Rima El-Sayed1,2, Vaidhehi Veena Sanmugananthan1,2, Joshua C Cheng1,2

  • 1Institute of Medical Science, University of Toronto, Toronto, ON, Canada.

Pain
|September 2, 2025
PubMed
概括

大脑中的阿尔法振荡会根据位置改变疼痛. 这项研究揭示了阿尔法脑波与疼痛调节之间的联系,

关键词:
阿尔法振荡有条件的疼痛调节磁脑摄影性别差异一个dlpfc美国

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Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
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