来自各种临床来源的大肠杆菌的抗菌敏感性模式
Waleed A Al Qahtani1, Mohamed S Zaghlol2, Yazeed Ali Mohammed Qasem1
1Laboratory Department, Armed Force Hospital, Jazan, Kingdom of Saudi Arabia.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|September 2, 2025
概括
大肠杆菌 (E. coli) 感染对常见的抗生素如诺夫洛克萨辛和安皮西林具有高耐药性. 然而,大肠杆菌对阿米卡辛,提格环素和伊米仍然敏感,这表明有有效的治疗方案.
科学领域:
- 微生物学
- 传染性疾病
- 抗菌药物耐药性
背景情况:
- 大肠杆菌 (E. coli) 是一种常见的细菌,在人类和动物的胃肠道和环境中发现.
- 大肠杆菌可以引起各种感染,因此需要了解其抗菌敏感性模式.
研究的目的:
- 从贾赞地区的临床样本中确定大肠杆菌分离物的患病率和抗菌敏感性.
- 评估大肠杆菌在尿液,伤口和唾液样本中的频率.
主要方法:
- 在贾赞地区的多个中心进行了回顾性横截面研究.
- 从2023年1月到2023年12月的数据包括来自各种临床标本的大肠杆菌分离物的培养和抗菌敏感性测试.
主要成果:
- 大肠杆菌最常从尿样 (85. 49%) 中分离出来,其次是 (9. 06%) 和唾液 (5. 45%).
- 对于阿米卡辛 (97. 49%),提格环素 (90. 87%) 和伊米 (90. 35%) 观察到高敏感率.
- 相反,诺夫洛克萨辛 (93. 67%),安皮西林 (79. 60%) 和塞福 (71. 65%) 的抗药率较高.
结论:
- 在Jazan地区的大肠杆菌分离物中观察到显著的抗生素耐药性.
- 在这种情况下,阿米卡辛,蒂格赛克林和Imipenem是有效的抗生素.
- 对常用抗生素如诺夫洛克萨辛,安皮西林和塞福胺的耐药性强调了需要仔细选择抗生素的必要性.
更多相关视频
09:44Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
2.3K
08:30One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures
Published on: July 9, 2012
25.6K
相关概念视频
01:26Urine Studies II: Urine Culture and Sensitivity Test
112
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
112
01:28Antimicrobial Effectiveness
156
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
156
01:30Development of Antibiotic Resistance
197
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
197