胆固醇衍生物通过结合细胞质子单元中的CARC和CRAC基因来调节基酶7的活性

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Updated: Sep 9, 2025

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
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Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Published on: January 27, 2014

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Radim Jaroušek1,2, Petra Dad'ová1,2, Alexandra Litvinchuk2

  • 1Department of Experimental Biology, Faculty of Science, Masaryk University, Kotlářská 2, 602 00 Brno, Czech Republic.

ACS omega
|September 2, 2025
PubMed
概括

胆固醇衍生物与细胞膜上腺环酶7 (AC7) 酶结合,从而降低它们的活性. 这一发现凸显了胆固醇衍生物作为AC7的潜在调节剂,影响细胞信号通路.

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