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影响手术前哨淋巴结的因素 乳腺癌的对比增强超声波
Yijie Dong1,2, Juan Liu1, Wanru Jia1
1Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Quantitative imaging in medicine and surgery
|September 2, 2025
概括
术前对照增强超声波检测哨兵淋巴结 (SLN-CEUS) 对于乳腺癌的分期至关重要. 淋巴结转移,患者年龄,瘤位置和表面距离独立影响SLN-CEUS结果.
科学领域:
- 癌症学
- 放射学
- 医学成像
背景情况:
- 在手术前对护卫淋巴结进行评估对于乳腺癌的治疗至关重要.
- 护卫淋巴结 (SLN) 是癌细胞扩散的第一个节点.
研究的目的:
- 确定影响术前皮肤间对比增强超声波 (SLN-CEUS) 检测乳腺癌患者哨戒淋巴结的准确性.
- 分析临床,组织病理和超声波特征与SLN-CEUS结果之间的相关性.
主要方法:
- 共有176名乳腺癌患者接受了手术前的SLN-CEUS治疗.
- SLN-CEUS结果分为阳性 (淋巴血管和SLN可见) 或阴性 (淋巴血管可见,SLN不可见;或没有可见).
- 在阳性和阴性组之间比较了临床特征,组织病理学,超声波特征和对比剂量.
主要成果:
- SLN-CEUS的诊断灵敏度为81.5%,特异性为90.7%,准确度为87.8%.
- 在SLN-CEUS结果与年龄,体质与体表面的距离 (DTS),瘤位置,病理和淋巴结转移之间发现了显著的相关性 (P<0.05).
- 逻辑回归确定了年龄,位置,DTS和淋巴结转移作为影响SLN-CEUS结果的独立因素.
结论:
- 淋巴结转移,患者年龄,瘤位置和DTS是影响负面SLN-CEUS结果的独立因素.
- SLN-CEUS是乳腺癌手术前哨淋巴结评估的一个有价值的工具.
- 了解这些影响因素可以优化SLN-CEUS解释和改善手术规划.
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