在Pitjantjatjara:澳大利亚原住民和托雷斯海峡岛民之间的随机交叉验证研究的协议
Matthew W R Stevens1, Sue Bertossa2, Dominic Barry3
1School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.
Contemporary clinical trials communications
|September 2, 2025
概括
这项研究验证了澳大利亚原住民使用Pitjantjatjara语言的酒精,吸烟和吸毒查测试 (ASSIST). 这些发现旨在支持文化安全的健康干预措施,并减少健康差异.
科学领域:
- 原住民的健康
- 药物成
- 医疗服务研究
背景情况:
- 毒品使用是澳大利亚的主要健康负担,由于历史和持续的创伤,
- 文化上合适且经过验证的查工具对于早期识别和支持有风险的个人至关重要.
- 现有的查工具可能不适合在土著语言中使用,造成了获得护理的障碍.
研究的目的:
- 验证使用Pitjantjatjara语言的酒精,吸烟和物质参与查测试 (ASSIST).
- 确保查工具在土著和托雷斯海峡岛民的文化上是可以接受的,有效的和可靠的.
- 促进与物质相关的危害的早期发现,并改善获得支持服务的机会.
主要方法:
- 这项研究从南澳大利亚的各种土著健康和福利机构招募了18至65岁的参与者.
- 参与者将通过iPad应用程序完成ASSIST工具, 并与Pitjantjatjara翻译进行半结构化诊断面试.
- 通过重复完成应用程序来评估可靠性,并通过高风险参与者的专业临床评估来检查有效性.
主要成果:
- 本节不适用,因为摘要描述了研究方案.
- 这项研究旨在生成Pitjantjatjara适应的ASSIST工具的有效性和可靠性.
- 结果将反映翻译查工具在识别物质使用障碍方面的有效性.
结论:
- 有效可靠的查工具对于解决与物质使用相关的危害至关重要.
- 通过成功验证Pitjantjatjara ASSIST工具,可以为社区主导的减少健康差距的努力做出重大贡献.
- 这种文化适应的工具有潜力通过解决土著社区可修改的风险因素来改善健康结果.
相关概念视频
01:16Crossover Experiments
3.0K
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
3.0K
01:13Randomized Experiments
7.2K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
7.2K
01:20Study Designs in Epidemiology
410
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
410
01:15Study Design in Statistics
8.5K
A study design is a set of techniques that allow a researcher to collect and analyze data from different variables defined for a specific research problem. Statistics is commonly for effective study design and more robust experiments,
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
8.5K
01:20Comparing the Survival Analysis of Two or More Groups
280
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
280
01:11Blinding
2.6K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.6K