眼癌负担的全球趋势和不平等:基于全球疾病负担的综合分析
Jianhao Bai1, Zhongqi Wan2, Yan Gao3
1Department of Ophthalmology, Shanghai East Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai, China.
Frontiers in medicine
|September 2, 2025
概括
全球眼癌负担正在增加,不同国家,年龄组和性别的发病率,患病率和死亡率存在显著差异. 针对性干预对于减少视力损失和癌症死亡至关重要.
科学领域:
- 眼科 眼科
- 癌症学
- 流行病学
背景情况:
- 眼部癌症对视力和生存构成重大威胁,因为它的位置,诊断挑战和攻击性.
- 目癌的全球流行病学数据,特别是不同国家,年龄和性别的差异,仍未得到充分研究.
研究的目的:
- 分析全球眼癌趋势,包括从1990年到2021年的发病率,患病率,死亡率和残疾调整寿命年 (DALYs).
- 调查全球眼癌负担的地理,社会人口,年龄和性别差异.
主要方法:
- 利用2021年全球疾病负担研究对204个国家的数据 (1990-2021年).
- 使用年龄标准化率和估计的年均百分比变化以评估时间趋势.
- 根据社会人口指数 (SDI),性别和年龄分析差异,使用度和斜率指数分析.
主要成果:
- 从1990年到2021年,全球眼癌发病率和患病率有所增加,地理和社会人口统计学的差异很大.
- 发达地区的患病率和发病率较高, 较不发达地区的死亡率和残疾负担较高.
- 年龄较大的人口 (≥65岁) 承担了最大的负担,男性的发病率/患病率普遍较高,而SDI较低的地区的妇女面临不成比例的死亡率.
结论:
- 全球眼癌患病负担存在显著差异,受社会人口因素,性别和年龄的影响.
- 紧急投资诊断基础设施和公平,性别敏感的护理是必要的.
- 需要采取干预措施来减少可预防的视力丧失和眼癌死亡率.
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