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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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动态交互的蛋白质网络提供了一种克服5'-单酸氧化的巨大内在障碍的机制

Pankaj Dubey1,2, Anish Somani2, Jessica Lin3

  • 1California Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, California 94720, United States.

ACS central science
|September 2, 2025
PubMed
概括

丁5'-单酸脱碳酶 (OMPDC) 使用特定的热网络来引导催化能量. 这些蛋白质网络将溶剂连接到活性部位,优化酶效率和基质结合.

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