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Updated: Sep 9, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

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防御性耐受性驱使潜入病原性B细胞的重编程和功能障碍,确保耐受性的维持

Koki Hayashi1,2,3, Takahiro Yokose1,2,3, Jenna Lancey1,2,3

  • 1Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital and Harvard Medical School; Boston, MA, USA.

Research square
|September 2, 2025
PubMed
概括

调控性B细胞 (Bregs) 不会导致移植耐受性. 相反,B细胞上的FcγRIIB和Siglec-G是移植接受和瘤免疫逃避的关键.

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In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

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