与单个药物相比,组合多种药物在临床规模的工作负载下保持准确性
Eyal Klang1,2,3, Mahmud Omar1,2,3, Ganesh Raut1
1The Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Medical Center, NY, USA.
medRxiv : the preprint server for health sciences
|September 2, 2025
概括
使用大型语言模型 (LLM) 编排的多代理系统保持临床工作负载的准确性和效率,在重任务负载下优于单代理方法.
科学领域:
- 人工智能
- 临床信息学
- 计算医学
背景情况:
- 大型语言模型 (LLM) 对临床应用有希望,但需要在现实的工作负载下进行评估.
- 在医疗保健环境中,LLM代理架构的可扩展性和性能尚未得到充分理解.
- 单剂LLM系统的异质临床任务带来了独特的挑战.
研究的目的:
- 为了比较单剂与多剂LLM系统的临床规模工作负载的性能.
- 在模拟临床流量的不同批量下评估LLM的准确性,效率和延迟.
- 在多个代理框架中评估任务隔离对LLM绩效的影响.
主要方法:
- 测试了两个LLM配置:单个代理和一个编排的多代理系统.
- 任务包括数据检索,提取和剂量计算,批量大小从5到80.
- 性能指标包括聚合精度,代币使用和延迟,分析了四个LLM检查点.
主要成果:
- 多代理系统在负载下保持高准确率 (90.6%在5个任务中,65.3%在80个任务中),而单代理系统的准确率急剧下降 (73.1%至16.6%).
- 在10个任务之外出现了显著的性能差异 (FDR调整后的p < 0.01).
- 与单个代理运行相比,多代理执行将令牌使用量减少了多达65倍,并限制了延迟增长.
结论:
- 对于临床规模的工作负载,LLM代理的轻量化编排是有效的.
- 与医疗保健中的单剂LLM相比,多剂系统提供了更高的准确性,效率和可审计性.
- 多代理设计中的任务隔离可以防止上下文干扰,并维持性能.
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