在海听力皮层中执行任务时的声音位置的动态表示
bioRxiv : the preprint server for biology
|September 2, 2025
概括
行为要求增强听觉皮层的响应, 不仅对有声音的位置, 也对无声音的位置. 这表明任务需求招募比以前理解的更广泛的神经网络.
科学领域:
- 神经科学
- 听觉神经科学
- 计算神经科学
背景情况:
- 听觉皮层中的神经反应是由行为目标调节的,例如对特定位置的注意.
- 感应场外 (RF) 刺激对神经活动和行为的影响仍然不太清楚.
研究的目的:
- 调查行为需求如何调节听觉皮层神经元的经典受体场 (RF) 外呈现的声音的神经反应.
- 探索与任务相关的空间感应场的神经机制.
主要方法:
- 在不同位置接受听觉刺激的训练,
- 用电生理记录来测量神经元发射速率和膜潜力.
- 一个计算规范化模型被用来模拟和理解观察到的神经调节.
主要成果:
- 大多数听觉皮质神经元在RF中显示出受理刺激的发射率增加.
- 任务要求对RF外的刺激产生了显著的促进,有时在被动倾听时会超过对RF中心刺激的反应.
- 这种非射频促进在尾部听觉区域比起面部和初级听觉皮层更为普遍.
- 广泛的抑制和超极化,与正常化模型相一致,被观察到非射频刺激.
结论:
- 行为任务招募的听觉神经元网络比被动听力中直接响应目标刺激的更广泛.
- 与任务相关的非射频刺激表明听觉皮层的空间受体场具有动态和适应性.
- 广泛的抑制在塑造神经反应和在听觉皮层中实现特定任务处理方面发挥着至关重要的作用.
更多相关视频
07:52Author Spotlight: Investigating Vocal Information Representation in Small Primates and Its Alteration by Psychiatric Disorders Using Noninvasive EEG
Published on: July 26, 2024
840
04:43Chronic Implantation of Whole-cortical Electrocorticographic Array in the Common Marmoset
Published on: February 1, 2019
9.8K
相关概念视频
Auditory Pathway
5.8K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.8K
Perceiving Loudness, Pitch, and Location
420
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
420
Hearing
53.0K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
53.0K
Perception of Sound Waves
4.6K
The human ear is not equally sensitive to all frequencies in the audible range. It may perceive sound waves with the same pressure but different frequencies as having different loudness. Moreover, the perception of sound waves depends on the health of an individual's ears, which decays with age. The health of one's ears may also be affected by regular exposure to loud noises.
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
4.6K
Auditory Perception
580
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the...
580
Motor and Sensory Areas of the Cortex
4.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.6K
