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Updated: Sep 9, 2025

De Novo Generation of Somatic Stem Cells by YAP/TAZ
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Published on: May 7, 2018

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在依赖于YAP1的恶性和再生性肝细胞重编程中需要SALL4

Minwook Kim, Yoojeong Park, Rachel Covitz

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    概括

    在肝脏疾病中,分裂性转录因子4 (SALL4) 调节肝细胞可塑性. 对于恶性转化为胆管癌至关重要,并影响再生重编程,成为潜在的治疗点.

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