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Updated: Apr 27, 2026

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高透量查和初步SAR研究发现一种新型的微粒级强效人体cGAS抑制剂

Jazmin Alarcón-Espósito, Ravi Kumar Nagiri, Siyu Wang

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
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    研究人员选了超过30万种化合物,以寻找循环GMP-AMP合成酶 (cGAS) 的抑制剂,这是神经炎症的关键因素. 他们发现了包括cpd6在内的强效药物候选,

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